β-Cyclodextrin 10.41-hydrate

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β-Cyclo­dextrin 10.41-hydrate

The crystal structure of β-cyclo-dextrin, C(42)H(70)O(35)·10.41H(2)O, consists of truncated cone-shaped β-cyclo-dextrin mol-ecules that are herringbone packed. The primary hydr-oxy groups form an intra-molecular hydrogen-bonded array. The semipolar cavity of the cyclo-dextrin host is filled with water mol-ecules, which show partial occupancy and disorder.

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Tf-lcbi130044 1032..1041

Post Graduate Program in Health Sciences, Faculty of Medicine, Federal University of Uberlândia, Minas Gerais, Brazil, Department of Internal Medicine, Faculty of Medicine, Federal University of Uberlândia, Minas Gerais, Brazil, Nutrition course, Faculty of Medicine, Federal University of Uberlândia, Minas Gerais, Brazil, Department of Pediatrics, Faculty of Medicine, Federal University of Uber...

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Encapsulation Mechanism of Oxyresveratrol by β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin and Computational Analysis.

In this study, the encapsulation mechanism of oxyresveratrol and β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) was studied. As this research shows, oxyresveratrol and two cyclodextrins (CDs) were able to form inclusion complexes in a 1:1 stoichiometry. However, the interaction with HP-β-CD was more efficient, showing up as higher encapsulation constant (KF) (35,864.72 ± 3415....

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Phase Solubility Studies on Oral Antidiabetic Drugs with Β-cyclodextrin and Hp - Β Cyclodextrin

Nateglinide(NTG), Repaglinide(RPG), and Glimepiride(GMP) are antidiabetic drugs. These antidiabetic drugs are poorly soluble in water, which affect the bioavailability. In the present work, complex formation of all the three drugs with b-cyclodextrin (b-CD) and Hydroxy propyl bcyclodextrin (HPb-CD) and then the possibility of improving the solubility of NTG, RPG and GMP by complexation with b-C...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2009

ISSN: 1600-5368

DOI: 10.1107/s160053680904865x